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Morphine Sulfate 200mg Tablets expose patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient’s risk prior to prescribing Morphine Sulfate Tablets, and monitor all patients regularly for the development of these behaviors and conditions
Accidental ingestion of even one dose of Morphine Sulfate Tablets, especially by children, can result in a fatal overdose of morphine
​Prolonged use of Morphine Sulfate Tablets during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available
When a patient who has been taking Morphine Sulfate Tablets regularly and may be physically dependent no longer requires therapy with Morphine Sulfate Tablets, taper the dose gradually, by 25% to 50% every 2 to 4 days, while monitoring carefully for signs and symptoms of withdrawal. If the patient develops these signs or symptoms, raise the dose to the previous level and taper more slowly, either by increasing the interval between dose decreases, decreasing the amount of change in dose, or both. Do not abruptly discontinue Morphine Sulfate Tablets in a physically-dependent patient Morphine Sulfate 200mg

When a patient who has been taking Morphine Sulfate Tablets regularly and may be physically dependent no longer requires therapy with the 200mg Tablets, taper the dose gradually, by 25% to 50% every 2 to 4 days, while monitoring carefully for signs and symptoms of withdrawal. If the patient develops these signs or symptoms, raise the dose to the previous level and taper more slowly, either by increasing the interval between dose decreases, decreasing the amount of change in dose, or both. Do not abruptly discontinue the 200mg Tablets in a physically-dependent patient