Description

Buy Arymo Er 30mg Online | Arymo Er 30mg (Morphine Sulfate)

Arymo Er 30mg (Morphine Sulfate) should be prescribed only by healthcare professionals who are knowledgeable in the use of potent opioids for the management of chronic pain.

A single dose of Arymo ER greater than 60 mg, or a total daily dose greater than 120 mg, are only for use in patients in whom tolerance to an opioid of comparable potency has been established. Patients who are opioid tolerant are those receiving, for one week or longer, at least 60 mg oral morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg oral oxycodone per day, 8 mg oral hydromorphone per day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone per day, or an equianalgesic dose of another opioid.

Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals
Initiate the dosing regimen for each patient individually, taking into account the patient’s severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse [see Warnings and Precautions (5.1)].
Monitor patients closely for respiratory depression, especially within the first 24-72 hours of initiating therapy and following dosage increases with Arymo ER and adjust the dosage accordingly
Instruct patients to take Arymo ER tablets whole, one tablet at a time, with enough water to ensure complete swallowing immediately after placing in the mouth Instruct patients not to pre-soak, lick, or otherwise wet the tablet prior to placing in the mouth Cutting, breaking, crushing, chewing, or dissolving Arymo ER tablets will result in uncontrolled delivery of morphine that could lead to overdose and death

Conversion from Parenteral Morphine or Other Opioids (Parenteral or Oral) to Arymo Er 30mg (Morphine Sulfate)

When converting from parenteral morphine or other non-morphine opioids (parenteral or oral) to Arymo ER, consider the following general points:

Parenteral to oral morphine ratio: Between 2 to 6 mg of oral morphine may be required to provide analgesia equivalent to 1 mg of parenteral morphine. Typically, a dose of morphine that is approximately three times the previous daily parenteral morphine requirement is sufficient.

Other parenteral or oral non-morphine opioids to oral morphine sulfate: Specific recommendations are not available because of a lack of systematic evidence for these types of analgesic substitutions. Published relative potency data are available, but such ratios are approximations. In general, begin with half of the estimated daily morphine requirement as the initial dose, managing inadequate analgesia by supplementation with immediate-release morphine.
Conversion from Methadone to Arymo ER

Close monitoring is of particular importance when converting methadone to other opioid agonists. The ratio between methadone and other opioid agonists may vary widely as a function of previous dose exposure. Methadone has a long half-life and can accumulate in the plasma.